6Q2Q
Crystal structure of mouse viperin bound to uridine triphosphate and S-adenosylhomocysteine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Radical S-adenosyl methionine domain-containing protein 2 | polymer | 318 | 36694.7 | 2 | UniProt (Q8CBB9) Pfam (PF13353) Pfam (PF04055) In PDB | Mus musculus (Mouse) | Viperin,Virus inhibitory protein,endoplasmic reticulum-associated,interferon-inducible |
2 | A, B | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
3 | A, B | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
5 | A, B | URIDINE 5'-TRIPHOSPHATE | non-polymer | 484.1 | 2 | Chemie (UTP) | |||
6 | A | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
7 | water | water | 18.0 | 756 | Chemie (HOH) |
Sequence modifications
A, B: 45 - 362 (UniProt: Q8CBB9)
PDB | External Database | Details |
---|---|---|
Leu 55 | Pro 55 | conflict |
Glu 57 | Asp 57 | conflict |
Arg 70 | Pro 70 | conflict |
Ala 261 | Glu 261 | engineered mutation |
Ala 266 | Glu 266 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 73389.4 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2864.5 | |
All* | Total formula weight | 76253.9 |