6Q1P
Glucocerebrosidase in complex with pharmacological chaperone norIMX8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glucosylceramidase | polymer | 497 | 55640.2 | 2 | UniProt (B2R6A7) Pfam (PF02055) Pfam (PF17189) UniProt (by SIFTS) (P04062) | Homo sapiens (Human) | Glucocerebrosidase |
| 2 | C, E (C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D (D) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 4 | AA, BA, CA, DA, F... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 16 | Chemie (EDO) | |||
| 5 | EA, FA, GA, HA, IA... (B, A) | SULFATE ION | non-polymer | 96.1 | 16 | Chemie (SO4) | |||
| 6 | OA, U (B, A) | (2S,3S,4S,5R)-2-{[(4-methylpentyl)sulfonyl]methyl}piperidine-3,4,5-triol | non-polymer | 295.4 | 2 | Chemie (P8Y) | |||
| 7 | V, W (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 8 | PA, QA (A, B) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111280.3 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1216.2 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 3563.3 | |
| All* | Total formula weight | 116059.8 |
