6Q0S

Crystal Structure of RSV strain B18537 Prefusion-stabilized glycoprotein F Variant DS-Cav1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (F)	Fusion glycoprotein F0	polymer	550	61307.1	1	UniProt (P13843) Pfam (PF00523)	Human respiratory syncytial virus (subgroup B / strain 18537)
2	B, C (F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D, E, F (F)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4	G (F)	water	water		18.0	263	Chemie (HOH)

Sequence modifications

F: 1 - 513 (UniProt: P13843)

PDB	External Database	Details
Cys 155	Ser 155	engineered mutation
Phe 190	Ser 190	engineered mutation
Leu 207	Val 207	engineered mutation
Cys 290	Ser 290	engineered mutation
Ser 514	-	expression tag
Ala 515	-	expression tag
Ile 516	-	expression tag
Gly 517	-	expression tag
Gly 518	-	expression tag
Tyr 519	-	expression tag
Ile 520	-	expression tag
Pro 521	-	expression tag
Glu 522	-	expression tag
Ala 523	-	expression tag
Pro 524	-	expression tag
Arg 525	-	expression tag
Asp 526	-	expression tag
Gly 527	-	expression tag
Gln 528	-	expression tag
Ala 529	-	expression tag
Tyr 530	-	expression tag
Val 531	-	expression tag
Arg 532	-	expression tag
Lys 533	-	expression tag
Asp 534	-	expression tag
Gly 535	-	expression tag
Glu 536	-	expression tag
Trp 537	-	expression tag
Val 538	-	expression tag
Leu 539	-	expression tag
Leu 540	-	expression tag
Ser 541	-	expression tag
Thr 542	-	expression tag
Phe 543	-	expression tag
Leu 544	-	expression tag
Gly 545	-	expression tag
Gly 546	-	expression tag
Leu 547	-	expression tag
Val 548	-	expression tag
Pro 549	-	expression tag
Arg 550	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	61307.1
Non-Polymers*	Number of molecules	5
	Total formula weight	730.6
All*	Total formula weight	62037.7

*Water molecules are not included.