6PZF

Crystal structure of human NA-63 Fab in complex with neuraminidase from A/Hunan/02650/2016(H7N9)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Neuraminidase	polymer	393	43983.0	2	Pfam (PF00064) UniProt (by SIFTS) (R4NFR6) In PDB	Influenza A virus (A/Hunan/02650/2016(H7N9)
2	E, L	NA-63 Fab light chain	polymer	216	23547.1	2		Homo sapiens (Human)
3	F, H	NA-63 Fab heavy chain	polymer	228	24491.3	2		Homo sapiens (Human)
4	C, D	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1883.7	2	In PDB GlyTouCan (G60230HH)
5	G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	B, A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
8	B, A	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
9		water	water		18.0	76	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	184042.8
Branched	Number of molecules	3
	Total formula weight	4191.7
Non-Polymers*	Number of molecules	8
	Total formula weight	902.5
All*	Total formula weight	189136.9

*Water molecules are not included.