Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6PZ3

Polymerase Eta-catalyzed insertion of correct G opposite template cytarabine (AraC) residue

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548645.81UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(P)
DNA Primer strandpolymer82426.61synthetic construct
3C
(T)
DNA template containing cytarabine (AraC) residuepolymer123638.41synthetic construct
4D
(A)
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosinenon-polymer506.21Chemie (XG4)
5E, F
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7H, I, J
(A, P, T)
waterwater18.0123Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Met 406Cys 406engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54710.8
Non-Polymers*Number of molecules4
Total formula weight646.9
All*Total formula weight55357.7
*Water molecules are not included.

239149

PDB entries from 2025-07-23

PDB statisticsPDBj update infoContact PDBjnumon