6PXC
N-Terminal SH2 domain of the p120RasGAP bound to a p190RhoGAP phosphotyrosine peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ras GTPase-activating protein 1 | polymer | 109 | 12266.8 | 1 | UniProt (P20936) Pfam (PF00017) In PDB | Homo sapiens (Human) | RasGAP,Ras p21 protein activator,p120GAP |
2 | U | phosphopeptide of p190RhoGAP | polymer | 14 | 1626.5 | 1 | UniProt (by SIFTS) (Q9NRY4) In PDB | Homo sapiens | |
3 | water | water | 18.0 | 56 | Chemie (HOH) |
Sequence modifications
A: 174 - 280 (UniProt: P20936)
PDB | External Database | Details |
---|---|---|
Gly 172 | - | expression tag |
Ser 173 | - | expression tag |
Ser 236 | Cys 236 | engineered mutation |
Ser 261 | Cys 261 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 13893.4 | |
All* | Total formula weight | 13893.4 |