6PWC
A complex structure of arrestin-2 bound to neurotensin receptor 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (R) | Neurotensin receptor type 1 | polymer | 370 | 41555.4 | 1 | UniProt (P30989) Pfam (PF00001) | Homo sapiens (Human) | NTR1,High-affinity levocabastine-insensitive neurotensin receptor,NTRH |
| 2 | B (B) | Neurotensin peptide | polymer | 6 | 819.0 | 1 | synthetic construct | ||
| 3 | C (A) | Beta-arrestin-1 | polymer | 393 | 44161.4 | 1 | UniProt (P49407) Pfam (PF00339) Pfam (PF02752) | Homo sapiens (Human) | Arrestin beta-1,Non-visual arrestin-2 |
| 4 | D (H) | Fab30 heavy chain | polymer | 238 | 25689.6 | 1 | synthetic construct | ||
| 5 | E (L) | Fab30 light chain | polymer | 215 | 23435.1 | 1 | synthetic construct |
Sequence modifications
A: 1 - 393 (UniProt: P49407)
| PDB | External Database | Details |
|---|---|---|
| Cys 81 | Val 81 | conflict |
| Cys 279 | Ala 279 | conflict |
| Ala 386 | Ile 386 | conflict |
| Ala 387 | Val 387 | conflict |
| Ala 388 | Phe 388 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 135660.5 | |
| All* | Total formula weight | 135660.5 |
