6PWC
A complex structure of arrestin-2 bound to neurotensin receptor 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | R | Neurotensin receptor type 1 | polymer | 370 | 41555.4 | 1 | UniProt (P30989) Pfam (PF00001) In PDB | Homo sapiens (Human) | NTR1,High-affinity levocabastine-insensitive neurotensin receptor,NTRH |
2 | B | Neurotensin peptide | polymer | 6 | 819.0 | 1 | synthetic construct | ||
3 | A | Beta-arrestin-1 | polymer | 393 | 44161.4 | 1 | UniProt (P49407) Pfam (PF00339) Pfam (PF02752) In PDB | Homo sapiens (Human) | Arrestin beta-1,Non-visual arrestin-2 |
4 | H | Fab30 heavy chain | polymer | 238 | 25689.6 | 1 | synthetic construct | ||
5 | L | Fab30 light chain | polymer | 215 | 23435.1 | 1 | synthetic construct |
Sequence modifications
A: 1 - 393 (UniProt: P49407)
PDB | External Database | Details |
---|---|---|
Cys 81 | Val 81 | conflict |
Cys 279 | Ala 279 | conflict |
Ala 386 | Ile 386 | conflict |
Ala 387 | Val 387 | conflict |
Ala 388 | Phe 388 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 135660.5 | |
All* | Total formula weight | 135660.5 |