6PV9
Human PD-L1 bound to a macrocyclic peptide which blocks the PD-1/PD-L1 interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Programmed cell death 1 ligand 1 | polymer | 222 | 25456.9 | 1 | UniProt (Q9NZQ7) Pfam (PF07686) Pfam (PF08205) | Homo sapiens (Human) | PD-L1, Programmed death ligand 1, B7 homolog 1, B7-H1 |
| 2 | B (B) | macrocyclic peptide | polymer | 17 | 1839.2 | 1 | synthetic construct | ||
| 3 | C, D (A, B) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 19 - 239 (UniProt: Q9NZQ7)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27296.1 | |
| All* | Total formula weight | 27296.1 |
