6PUL
Structure of human MAIT A-F7 TCR in complex with human MR1 3'D-5-OP-RU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, D (B, D) | TRA@ protein | polymer | 204 | 22781.3 | 2 | Homo sapiens (Human) | ||
| 3 | E, G (E, G) | Human TCR beta chain | polymer | 246 | 27677.8 | 2 | Homo sapiens | ||
| 4 | F, H (F, H) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 5 | I, J, L, N, Q... (A, B, D, F, G) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 6 | K, M (A, C) | 1,3-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol | non-polymer | 314.3 | 2 | Chemie (Q81) | |||
| 7 | O (E) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 8 | P, S, T, V, W (E, F, G, H) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 9 | AA, BA, CA, DA, EA... (D, E, F, G, H...) | water | water | 18.0 | 1794 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
F, H: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188100.1 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1447.2 | |
| All* | Total formula weight | 189547.3 |
