6PTS
NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Apolipoprotein A-I | polymer | 198 | 23080.1 | 2 | UniProt (P02647) Pfam (PF01442) | Homo sapiens (Human) | Membrane Scaffold Protein, ApoA-I, Apolipoprotein A1 |
| 2 | C (B) | GTPase KRas | polymer | 185 | 21116.1 | 1 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 3 | D (D) | RAF proto-oncogene serine/threonine-protein kinase | polymer | 132 | 15266.9 | 1 | UniProt (P04049) Pfam (PF02196) Pfam (PF00130) | Homo sapiens (Human) | Proto-oncogene c-RAF,cRaf,Raf-1 |
| 4 | AA, AC, BA, BB, BC... (C, D, B, A) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 64 | Chemie (PCW) | |||
| 5 | AB, CC, DC, EC, FC... (C, D, A, B) | O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine | non-polymer | 788.0 | 16 | Chemie (17F) | |||
| 6 | QB (B) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 7 | RB (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 8 | IC, JC (D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
D: 356 - 487 (UniProt: P04049)
| PDB | External Database | Details |
|---|---|---|
| Gln 403 | His 103 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 82543.3 | |
| Non-Polymers* | Number of molecules | 84 |
| Total formula weight | 63661.8 | |
| All* | Total formula weight | 146205.1 |
