6PTH

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Pseudomonas aeruginosa bound to griselimycin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Beta sliding clamp	polymer	463	51843.8	1	UniProt (Q9I7C4) Pfam (PF00712) Pfam (PF02767) Pfam (PF02768)	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	Sliding clamp,Beta-clamp processivity factor,DNA polymerase III beta sliding clamp subunit,DNA polymerase III subunit beta
2	B (G)	Griselimycin	polymer	11	1115.4	1	BIRD (PRD_002311)	Streptomyces griseus	ACE-MVA-MP8-NCZ-LEU-MP8-LEU-MVA-PRO-MLU-GLY
3	C (A)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	D (A)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

A: 1 - 367 (UniProt: Q9I7C4)

PDB	External Database	Details
Met -95	-	initiating methionine
Gly -94	-	expression tag
His -93	-	expression tag
His -92	-	expression tag
His -91	-	expression tag
His -90	-	expression tag
His -89	-	expression tag
His -88	-	expression tag
Ser -87	-	expression tag
Gly -86	-	expression tag
Glu -85	-	expression tag
Val -84	-	expression tag
Lys -83	-	expression tag
Pro -82	-	expression tag
Glu -81	-	expression tag
Val -80	-	expression tag
Lys -79	-	expression tag
Pro -78	-	expression tag
Glu -77	-	expression tag
Thr -76	-	expression tag
His -75	-	expression tag
Ile -74	-	expression tag
Asn -73	-	expression tag
Leu -72	-	expression tag
Lys -71	-	expression tag
Val -70	-	expression tag
Ser -69	-	expression tag
Asp -68	-	expression tag
Gly -67	-	expression tag
Ser -66	-	expression tag
Ser -65	-	expression tag
Glu -64	-	expression tag
Ile -63	-	expression tag
Phe -62	-	expression tag
Phe -61	-	expression tag
Lys -60	-	expression tag
Ile -59	-	expression tag
Lys -58	-	expression tag
Lys -57	-	expression tag
Thr -56	-	expression tag
Thr -55	-	expression tag
Pro -54	-	expression tag
Leu -53	-	expression tag
Arg -52	-	expression tag
Arg -51	-	expression tag
Leu -50	-	expression tag
Met -49	-	expression tag
Glu -48	-	expression tag
Ala -47	-	expression tag
Phe -46	-	expression tag
Ala -45	-	expression tag
Lys -44	-	expression tag
Arg -43	-	expression tag
Gln -42	-	expression tag
Gly -41	-	expression tag
Lys -40	-	expression tag
Glu -39	-	expression tag
Met -38	-	expression tag
Asp -37	-	expression tag
Ser -36	-	expression tag
Leu -35	-	expression tag
Arg -34	-	expression tag
Phe -33	-	expression tag
Leu -32	-	expression tag
Tyr -31	-	expression tag
Asp -30	-	expression tag
Gly -29	-	expression tag
Ile -28	-	expression tag
Arg -27	-	expression tag
Ile -26	-	expression tag
Gln -25	-	expression tag
Ala -24	-	expression tag
Asp -23	-	expression tag
Gln -22	-	expression tag
Thr -21	-	expression tag
Pro -20	-	expression tag
Glu -19	-	expression tag
Asp -18	-	expression tag
Leu -17	-	expression tag
Asp -16	-	expression tag
Met -15	-	expression tag
Glu -14	-	expression tag
Asp -13	-	expression tag
Asn -12	-	expression tag
Asp -11	-	expression tag
Ile -10	-	expression tag
Ile -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
His -6	-	expression tag
Arg -5	-	expression tag
Glu -4	-	expression tag
Gln -3	-	expression tag
Ile -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	52959.3
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	53055.3

*Water molecules are not included.