6PRA
S. aureus dihydrofolate reductase with NADP(H) and empty folate pocket
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dihydrofolate reductase | polymer | 163 | 18742.5 | 1 | UniProt (P0A017) Pfam (PF00186) In PDB | Staphylococcus aureus | DHFR |
| 2 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 0 - 158 (UniProt: P0A017)
| PDB | External Database | Details |
|---|---|---|
| Leu 159 | - | expression tag |
| Val 160 | - | expression tag |
| Pro 161 | - | expression tag |
| Arg 162 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18742.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 927.6 | |
| All* | Total formula weight | 19670.1 |
