6PQ8
Crystal structure of TLA-1 S70G extended spectrum Beta-lactamase in complex with clavulanic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 299 | 33342.3 | 1 | UniProt (Q9X6W1) Pfam (PF13354) | Escherichia coli | |
| 2 | B (A) | ASPARTIC ACID | non-polymer | 133.1 | 1 | Chemie (ASP) | |||
| 3 | C (A) | (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID | non-polymer | 199.2 | 1 | Chemie (J01) | |||
| 4 | D, F, G, H, J... (A) | ACETATE ION | non-polymer | 59.0 | 8 | Chemie (ACT) | |||
| 5 | E, I (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | N, O, P, Q (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 7 | R (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | S (A) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence modifications
A: 2 - 292 (UniProt: Q9X6W1)
| PDB | External Database | Details |
|---|---|---|
| Gly 70 | Ser 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33342.3 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1408.5 | |
| All* | Total formula weight | 34750.8 |
