6PMH

Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	UDP-glucose 4-epimerase related protein	polymer	368	41973.2	1	UniProt (O26475) Pfam (PF01370)	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
2	B (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
3	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E, F (A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5	G (A)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	1	Chemie (UDP)
6	H (A)	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP)
7	I (A)	water	water		18.0	262	Chemie (HOH)

Sequence modifications

A: 1 - 332 (UniProt: O26475)

PDB	External Database	Details
Met -35	-	initiating methionine
Arg -34	-	expression tag
Gly -33	-	expression tag
Ser -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Gly -25	-	expression tag
Met -24	-	expression tag
Ala -23	-	expression tag
Ser -22	-	expression tag
Met -21	-	expression tag
Thr -20	-	expression tag
Gly -19	-	expression tag
Gly -18	-	expression tag
Gln -17	-	expression tag
Gln -16	-	expression tag
Met -15	-	expression tag
Gly -14	-	expression tag
Arg -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Tyr -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
His -3	-	expression tag
Pro -2	-	expression tag
Phe -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41973.2
Non-Polymers*	Number of molecules	7
	Total formula weight	1101.4
All*	Total formula weight	43074.7

*Water molecules are not included.