6PMH

Structure of Epimerase Mth375 from the thermophilic pseudomurein-containing methanogen Methanothermobacter thermautotrophicus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0008460	molecular_function	dTDP-glucose 4,6-dehydratase activity
A	0010253	biological_process	UDP-rhamnose biosynthetic process
A	0010280	molecular_function	UDP-L-rhamnose synthase activity
A	0010315	biological_process	auxin export across the plasma membrane
A	0050377	molecular_function	UDP-glucose 4,6-dehydratase activity
A	0051555	biological_process	flavonol biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue PO4 A 401

Chain	Residue
A	ASN43
A	HOH662
A	SER45
A	HIS88
A	VAL104
A	AMP407
A	HOH510
A	HOH541
A	HOH635
A	HOH637

---

site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 402

Chain	Residue
A	ALA90
A	ASN91
A	GLN92
A	ASN93
A	TYR195
A	TRP283
A	GOL403
A	UDP406
A	HOH501

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 403

Chain	Residue
A	ASN91
A	SER129
A	TYR155
A	ASN197
A	GOL402
A	UDP406
A	HOH530
A	HOH544

---

site_id	AC4
Number of Residues	2
Details	binding site for residue CL A 404

Chain	Residue
A	SER148
A	HOH708

---

site_id	AC5
Number of Residues	2
Details	binding site for residue CL A 405

Chain	Residue
A	ARG241
A	GLU242

---

site_id	AC6
Number of Residues	22
Details	binding site for residue UDP A 406

Chain	Residue
A	ASN91
A	CME131
A	ASN184
A	ASN197
A	VAL198
A	PHE202
A	PRO213
A	ILE214
A	THR215
A	ARG222
A	VAL258
A	ARG281
A	ASP284
A	GOL402
A	GOL403
A	HOH516
A	HOH523
A	HOH552
A	HOH558
A	HOH564
A	HOH592
A	HOH608

---

site_id	AC7
Number of Residues	23
Details	binding site for residue AMP A 407

Chain	Residue
A	GLY18
A	GLY21
A	ASP42
A	ASN43
A	LEU44
A	SER45
A	SER46
A	SER47
A	GLY63
A	ASP64
A	ILE65
A	LEU85
A	ALA86
A	ALA87
A	PHE89
A	VAL104
A	ARG196
A	PO4401
A	HOH517
A	HOH571
A	HOH596
A	HOH649
A	HOH668

---