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6PK6

Human PRPF4B bound to benzothiophene inhibitor 329

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASerine/threonine-protein kinase PRP4 homologpolymer35140949.31UniProt (Q13523)
Pfam (PF00069)
In PDB
Homo sapiens (Human)PRP4 kinase,PRP4 pre-mRNA-processing factor 4 homolog
2ASULFATE IONnon-polymer96.11Chemie (SO4)
3A4-(5-{[(2-aminophenyl)methyl]carbamoyl}thiophen-2-yl)-1-benzothiophene-2-carboxamidenon-polymer407.51Chemie (OND)
4waterwater18.0141Chemie (HOH)
Sequence modifications
A: 657 - 1005 (UniProt: Q13523)
PDBExternal DatabaseDetails
Ser 655-expression tag
Met 656-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40949.3
Non-Polymers*Number of molecules2
Total formula weight503.6
All*Total formula weight41452.9
*Water molecules are not included.

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PDB entries from 2024-07-17

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