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6PHA

Protein Tyrosine Phosphatase 1B (1-301), F182A mutant, vanadate bound state

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ATyrosine-protein phosphatase non-receptor type 1polymer29734513.31UniProt (P18031)
Pfam (PF00102)
In PDB
Homo sapiens (Human)Protein-tyrosine phosphatase 1B,PTP-1B
2AVANADATE IONnon-polymer114.91Chemie (VO4)
3AGLYCEROLnon-polymer92.15Chemie (GOL)
4AACETATE IONnon-polymer59.03Chemie (ACT)
5waterwater18.0152Chemie (HOH)
Sequence modifications
A: 2 - 298 (UniProt: P18031)
PDBExternal DatabaseDetails
Ala 182Phe 182engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34513.3
Non-Polymers*Number of molecules9
Total formula weight752.5
All*Total formula weight35265.8
*Water molecules are not included.

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PDB entries from 2024-07-24

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