6PGR
Cocomplex structure of Deoxyhypusine synthase with inhibitor 6-BROMO-N-(1H-INDOL-4-YL)-1-BENZOTHIOPHENE-2-CARBOXAMIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Deoxyhypusine synthase | polymer | 372 | 41213.6 | 2 | UniProt (P49366) Pfam (PF01916) | Homo sapiens (Human) | DHS |
| 2 | C, D (A, B) | 6-bromo-N-(1H-indol-4-yl)-1-benzothiophene-2-carboxamide | non-polymer | 371.3 | 2 | Chemie (8XY) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 369 (UniProt: P49366)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82427.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 742.5 | |
| All* | Total formula weight | 83169.7 |
