6PFN

Succinyl-CoA synthase from Francisella tularensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Succinate--CoA ligase [ADP-forming] subunit alpha	polymer	296	30950.6	2	UniProt (A0A454XSD0) Pfam (PF02629) Pfam (PF00549) UniProt (by SIFTS) (Q5NHF4)	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	Succinyl-CoA synthetase subunit alpha,SCS-alpha
2	B, D (B, D)	Succinate--CoA ligase [ADP-forming] subunit beta	polymer	387	41620.6	2	UniProt (Q5NHF3) Pfam (PF08442) Pfam (PF00549)	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	Succinyl-CoA synthetase subunit beta,SCS-beta
3	E, F (A, C)	COENZYME A	non-polymer		767.5	2	Chemie (COA)
4	G (D)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
5	H (D)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
6	I, J, K, L (A, B, C, D)	water	water		18.0	802	Chemie (HOH)

Sequence modifications

A, C: 1 - 290 (UniProt: A0A454XSD0)

PDB	External Database	Details
Val 85	Ala 85	engineered mutation
Glu 291	-	expression tag
Asn 292	-	expression tag
Leu 293	-	expression tag
Tyr 294	-	expression tag
Phe 295	-	expression tag
Gln 296	-	expression tag

B, D: 1 - 387 (UniProt: Q5NHF3)

PDB	External Database	Details
Thr 69	Ala 69	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	145142.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1656.2
All*	Total formula weight	146798.6

*Water molecules are not included.