6PFN
Succinyl-CoA synthase from Francisella tularensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
| A | 0004776 | molecular_function | succinate-CoA ligase (GDP-forming) activity |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0009361 | cellular_component | succinate-CoA ligase complex (ADP-forming) |
| A | 0016874 | molecular_function | ligase activity |
| A | 0042709 | cellular_component | succinate-CoA ligase complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
| B | 0004776 | molecular_function | succinate-CoA ligase (GDP-forming) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0006104 | biological_process | succinyl-CoA metabolic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0042709 | cellular_component | succinate-CoA ligase complex |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
| C | 0004776 | molecular_function | succinate-CoA ligase (GDP-forming) activity |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0009361 | cellular_component | succinate-CoA ligase complex (ADP-forming) |
| C | 0016874 | molecular_function | ligase activity |
| C | 0042709 | cellular_component | succinate-CoA ligase complex |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004775 | molecular_function | succinate-CoA ligase (ADP-forming) activity |
| D | 0004776 | molecular_function | succinate-CoA ligase (GDP-forming) activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0006104 | biological_process | succinyl-CoA metabolic process |
| D | 0016874 | molecular_function | ligase activity |
| D | 0042709 | cellular_component | succinate-CoA ligase complex |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue COA A 500 |
| Chain | Residue |
| A | GLY15 |
| A | TYR72 |
| A | VAL73 |
| A | PRO74 |
| A | SER81 |
| A | ILE96 |
| A | THR97 |
| A | GLU98 |
| A | ASN123 |
| A | CYS124 |
| A | PRO125 |
| A | THR17 |
| A | ILE137 |
| A | HOH612 |
| A | HOH623 |
| A | HOH639 |
| A | HOH667 |
| A | HOH678 |
| A | HOH688 |
| A | HOH717 |
| A | HOH732 |
| A | HOH744 |
| A | GLY18 |
| A | HOH754 |
| A | HOH766 |
| A | LYS19 |
| A | ASN20 |
| A | VAL39 |
| A | THR40 |
| A | PRO41 |
| A | LYS43 |
| site_id | AC2 |
| Number of Residues | 34 |
| Details | binding site for residue COA C 500 |
| Chain | Residue |
| C | GLY15 |
| C | THR17 |
| C | GLY18 |
| C | LYS19 |
| C | ASN20 |
| C | VAL39 |
| C | THR40 |
| C | PRO41 |
| C | LYS43 |
| C | TYR72 |
| C | VAL73 |
| C | PRO74 |
| C | SER81 |
| C | ILE96 |
| C | THR97 |
| C | GLU98 |
| C | ASN123 |
| C | CYS124 |
| C | PRO125 |
| C | ILE137 |
| C | HOH602 |
| C | HOH610 |
| C | HOH614 |
| C | HOH615 |
| C | HOH626 |
| C | HOH637 |
| C | HOH665 |
| C | HOH666 |
| C | HOH680 |
| C | HOH684 |
| C | HOH690 |
| C | HOH695 |
| C | HOH697 |
| C | HOH706 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue ACT D 501 |
| Chain | Residue |
| D | HIS227 |
| D | PRO228 |
| D | LYS229 |
| D | LEU230 |
| D | HOH689 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 502 |
| Chain | Residue |
| C | LEU106 |
| C | VAL107 |
| D | PRO152 |
| D | TYR186 |
| D | HOH619 |
| D | HOH678 |
Functional Information from PROSITE/UniProt
| site_id | PS00399 |
| Number of Residues | 14 |
| Details | SUCCINYL_COA_LIG_2 ATP-citrate lyase / succinyl-CoA ligases family active site. GvtAppgk...RMGHAG |
| Chain | Residue | Details |
| A | GLY236-GLY249 |
| site_id | PS01216 |
| Number of Residues | 30 |
| Details | SUCCINYL_COA_LIG_1 ATP-citrate lyase / succinyl-CoA ligases family signature 1. SRSGTLTyEavaqttklgfGqstcIGIGGD |
| Chain | Residue | Details |
| A | SER152-ASP181 |
| site_id | PS01217 |
| Number of Residues | 26 |
| Details | SUCCINYL_COA_LIG_3 ATP-citrate lyase / succinyl-CoA ligases family signature 3. GnIgcMvNGAGLAmatmDiIqlygGK |
| Chain | Residue | Details |
| B | GLY258-LYS283 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI7 |
| Number of Residues | 472 |
| Details | Domain: {"description":"ATP-grasp","evidences":[{"source":"HAMAP-Rule","id":"MF_00558","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00558","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
