6PFL
Crystal structure of Human HUWE1 WWE domain in complex with ADPR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | E3 ubiquitin-protein ligase HUWE1 | polymer | 91 | 10519.6 | 2 | UniProt (Q7Z6Z7) Pfam (PF02825) In PDB | Homo sapiens (Human) | ARF-binding protein 1,ARF-BP1,HECT,UBA and WWE domain-containing protein 1,HECT-type E3 ubiquitin transferase HUWE1,Homologous to E6AP carboxyl terminus homologous protein 9,HectH9,Large structure of UREB1,LASU1,Mcl-1 ubiquitin ligase E3,Mule,Upstream regulatory element-binding protein 1,URE-binding protein 1 |
| 2 | A, B | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 2 | Chemie (APR) | |||
| 3 | A, B | UNKNOWN ATOM OR ION | non-polymer | 3 | Chemie (UNX) | ||||
| 4 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A, B: 1611 - 1700 (UniProt: Q7Z6Z7)
| PDB | External Database | Details |
|---|---|---|
| Gly 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21039.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1118.6 | |
| All* | Total formula weight | 22157.8 |
