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6PE8

Crystal structure of CD40/ABBV-323 FAB complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, H)
FAB Heavy chainpolymer22323748.62Homo sapiens (Human)
2B, D
(B, L)
FAB Light chainpolymer22024291.02Homo sapiens (Human)
3E, F
(T, U)
Tumor necrosis factor receptor superfamily member 5polymer17319187.42UniProt (P25942)
Pfam (PF00020)
Homo sapiens (Human)B-cell surface antigen CD40,Bp50,CD40L receptor,CDw40
4G, H, I, J
(T, U)
SULFATE IONnon-polymer96.14Chemie (SO4)
5K, L, M, N, O...
(A, B, H, L, T...)
waterwater18.0151Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight134454.0
Non-Polymers*Number of molecules4
Total formula weight384.3
All*Total formula weight134838.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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