6PBX

Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Potassium voltage-gated channel subfamily H member 1	polymer	846	96261.4	4	UniProt (Q63472) Pfam (PF13426) Pfam (PF00520) Pfam (PF00027) In PDB	Rattus norvegicus (Rat)	Ether-a-go-go potassium channel 1, r-eag, Voltage-gated potassium channel subunit Kv10.1
2	B, D, F, H	Calmodulin-1	polymer	149	16852.5	4	UniProt (P0DP23) Pfam (PF13499) In PDB	Homo sapiens (Human)

Sequence modifications

A, C, E, G: 14 - 773 (UniProt: Q63472)

PDB	External Database	Details
Met 12	-	expression tag
Ala 13	-	expression tag

A, C, E, G: 774 - 848 (UniProt: Q63472)

PDB	External Database	Details
Ser 849	-	expression tag
Asn 850	-	expression tag
Ser 851	-	expression tag
Leu 852	-	expression tag
Glu 853	-	expression tag
Val 854	-	expression tag
Leu 855	-	expression tag
Phe 856	-	expression tag
Gln 857	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	452455.9
All*	Total formula weight	452455.9

*Water molecules are not included.