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6PBO

Staphylococcus aureus Dihydrofolate reductase in complex with NADPH and UCP1232

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1XDihydrofolate reductasepolymer15718015.61UniProt (P0A017)
Pfam (PF00186)
In PDB
Staphylococcus aureusDHFR
2X(4-{6-[(2S)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-2H-1,3-benzodioxol-4-yl}phenyl)acetic acidnon-polymer444.51Chemie (O71)
3XTricyclic NADPHnon-polymer745.41Chemie (XNP)
4XNADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
5waterwater18.045Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight18015.6
Non-Polymers*Number of molecules3
Total formula weight1933.3
All*Total formula weight19948.9
*Water molecules are not included.

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PDB entries from 2024-07-17

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