6PBJ
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase with Gly190Pro mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phospho-2-dehydro-3-deoxyheptonate aldolase | polymer | 464 | 50868.5 | 2 | UniProt (A0A0T9FW33) Pfam (PF01474) UniProt (by SIFTS) (O53512) | Mycobacterium tuberculosis | 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase |
| 2 | C, M (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | D, E, F, N, O... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | G, Q (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | H, I, J, R, S... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 6 | K, U, V, W (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 7 | L (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | X, Y (A, B) | water | water | 18.0 | 529 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 462 (UniProt: A0A0T9FW33)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Pro 190 | Gly 190 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101736.9 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1707.6 | |
| All* | Total formula weight | 103444.5 |
