6PAY
Structure of HsICDH1:Mg(II):ICT:NADPH(50%) complex reveals structural basis for observation of half-sites reactivity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Isocitrate dehydrogenase [NADP] cytoplasmic | polymer | 414 | 46720.2 | 4 | UniProt (O75874) Pfam (PF00180) In PDB | Homo sapiens (Human) | IDH,Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, Isocitrate dehydrogenase 1 |
| 2 | A, B, C, D | ISOCITRIC ACID | non-polymer | 192.1 | 4 | Chemie (ICT) | |||
| 3 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | A | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 5 | A, B, D | FORMIC ACID | non-polymer | 46.0 | 7 | Chemie (FMT) | |||
| 6 | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 186880.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1933.3 | |
| All* | Total formula weight | 188814.2 |
