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6P70

X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
DNA-directed RNA polymerase subunit alphapolymer31535056.22UniProt (Q9Z9H6)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
UniProt (by SIFTS) (Q5SHR6)
Thermus thermophilusRNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2C
(C)
DNA-directed RNA polymerase subunit betapolymer1119125436.51UniProt (Q8RQE9)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
Pfam (PF04560)
Thermus thermophilusRNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3D
(D)
DNA-directed RNA polymerase subunit beta'polymer1524170997.41UniProt (Q8RQE8)
Pfam (PF04997)
Pfam (PF21668)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Thermus thermophilusRNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4E
(E)
DNA-directed RNA polymerase subunit omegapolymer9911533.31UniProt (A0A1J1EUF1)
Pfam (PF01192)
UniProt (by SIFTS) (Q8RQE7)
Thermus thermophilusRNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5F
(F)
RNA polymerase sigma factor SigApolymer42348598.01UniProt (Q72L95)
Pfam (PF00140)
Pfam (PF04542)
Pfam (PF04539)
Pfam (PF04545)
UniProt (by SIFTS) (Q5SKW1)
Thermus thermophilus
6G
(G)
DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3')polymer216360.11Escherichia coli
7H
(H)
DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3')polymer278362.41Escherichia coli
8I, L, M
(B, D, G)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
9J, K
(D)
ZINC IONnon-polymer65.42Chemie (ZN)
Sequence modifications
F: 1 - 423 (UniProt: Q72L95)
PDBExternal DatabaseDetails
Thr 46Ala 46conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight441400.1
Non-Polymers*Number of molecules5
Total formula weight203.7
All*Total formula weight441603.8
*Water molecules are not included.

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PDB entries from 2025-07-30

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