6P6Y
Crystal structure of voltage-gated sodium channel NavAb V100C/Q150C disulfide crosslinked mutant in the activated state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ion transport protein | polymer | 257 | 29768.3 | 1 | UniProt (A8EVM5) Pfam (PF00520) | Arcobacter butzleri (strain RM4018) | |
| 2 | B, C (A) | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE | non-polymer | 614.9 | 2 | Chemie (CPS) PubChem (16396400) PubChem (18397788) PubChem (177530666) PubChem (24883538) PubChem (50987450) PubChem (51028881) PubChem (51028882) PubChem (53393728) PubChem (44120060) PubChem (58528211) PubChem (44450441) PubChem (53229977) PubChem (457060) PubChem (3659871) PubChem (107670) PubChem (71774074) PubChem (90488808) PubChem (91746229) PubChem (91809267) PubChem (102565428) PubChem (122361936) PubChem (122362044) PubChem (9895216) PubChem (10371606) PubChem (131632459) PubChem (133645855) PubChem (137704711) PubChem (146159681) | |||
| 3 | D, E, F, G, H (A) | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 5 | Chemie (PX4) PubChem (26198) PubChem (87505) PubChem (5313082) |
Sequence modifications
A: 1001 - 1239 (UniProt: A8EVM5)
| PDB | External Database | Details |
|---|---|---|
| Met 983 | - | initiating methionine |
| Asp 984 | - | expression tag |
| Tyr 985 | - | expression tag |
| Lys 986 | - | expression tag |
| Asp 987 | - | expression tag |
| Asp 988 | - | expression tag |
| Asp 989 | - | expression tag |
| Asp 990 | - | expression tag |
| Lys 991 | - | expression tag |
| Gly 992 | - | expression tag |
| Ser 993 | - | expression tag |
| Leu 994 | - | expression tag |
| Val 995 | - | expression tag |
| Pro 996 | - | expression tag |
| Arg 997 | - | expression tag |
| Gly 998 | - | expression tag |
| Ser 999 | - | expression tag |
| His 1000 | - | expression tag |
| Cys 1100 | Val 100 | engineered mutation |
| Cys 1150 | Gln 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29768.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 4624.5 | |
| All* | Total formula weight | 34392.8 |
