6P54
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by ceftriaxone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Probable peptidoglycan D,D-transpeptidase PenA | polymer | 329 | 35326.3 | 2 | UniProt (P08149) Pfam (PF00905) | Neisseria gonorrhoeae | Penicillin-binding protein 2,PBP-2 |
| 2 | C (A) | ceftriaxone, bound form | non-polymer | 572.6 | 1 | Chemie (NZV) | |||
| 3 | D (B) | CEFOTAXIME, C3' cleaved, open, bound form | non-polymer | 397.4 | 1 | Chemie (CEF) | |||
| 4 | E (B) | Ceftriaxone | non-polymer | 554.6 | 1 | Chemie (9F2) | |||
| 5 | F (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | G, H (A, B) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A, B: 237 - 574 (UniProt: P08149)
| PDB | External Database | Details |
|---|---|---|
| Gly 232 | - | expression tag |
| Ser 233 | - | expression tag |
| Gly 234 | - | expression tag |
| Gly 235 | - | expression tag |
| Ala 236 | - | expression tag |
| Gly 297 | Ala 283 | conflict |
| - | Tyr 284 | deletion |
| - | Asp 285 | deletion |
| - | Pro 286 | deletion |
| - | Asn 287 | deletion |
| - | Arg 288 | deletion |
| - | Pro 289 | deletion |
| - | Gly 290 | deletion |
| - | Arg 291 | deletion |
| - | Ala 292 | deletion |
| - | Asp 293 | deletion |
| - | Ser 294 | deletion |
| - | Glu 295 | deletion |
| - | Gln 296 | deletion |
| - | Arg 297 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70652.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1630.7 | |
| All* | Total formula weight | 72283.2 |
