6P54
Crystal structure of transpeptidase domain of PBP2 from Neisseria gonorrhoeae acylated by ceftriaxone
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Probable peptidoglycan D,D-transpeptidase PenA | polymer | 329 | 35326.3 | 2 | UniProt (P08149) Pfam (PF00905) In PDB | Neisseria gonorrhoeae | Penicillin-binding protein 2,PBP-2 |
2 | A | ceftriaxone, bound form | non-polymer | 572.6 | 1 | Chemie (NZV) | |||
3 | B | CEFOTAXIME, C3' cleaved, open, bound form | non-polymer | 397.4 | 1 | Chemie (CEF) | |||
4 | B | Ceftriaxone | non-polymer | 554.6 | 1 | Chemie (9F2) | |||
5 | B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
6 | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A, B: 237 - 574 (UniProt: P08149)
PDB | External Database | Details |
---|---|---|
Gly 232 | - | expression tag |
Ser 233 | - | expression tag |
Gly 234 | - | expression tag |
Gly 235 | - | expression tag |
Ala 236 | - | expression tag |
Gly 297 | Ala 283 | conflict |
- | Tyr 284 | deletion |
- | Asp 285 | deletion |
- | Pro 286 | deletion |
- | Asn 287 | deletion |
- | Arg 288 | deletion |
- | Pro 289 | deletion |
- | Gly 290 | deletion |
- | Arg 291 | deletion |
- | Ala 292 | deletion |
- | Asp 293 | deletion |
- | Ser 294 | deletion |
- | Glu 295 | deletion |
- | Gln 296 | deletion |
- | Arg 297 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70652.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1630.7 | |
All* | Total formula weight | 72283.2 |