6P2P
Tetrameric structure of ACAT1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Sterol O-acyltransferase 1 | polymer | 594 | 69745.4 | 4 | UniProt (P35610) Pfam (PF03062) | Homo sapiens (Human) | Acyl-coenzyme A:cholesterol acyltransferase 1,ACAT-1,Cholesterol acyltransferase 1 |
| 2 | E, F, G, H (A, B, C, D) | S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | non-polymer | 1032.0 | 4 | Chemie (3VV) |
Sequence modifications
A, B, C, D: 1 - 550 (UniProt: P35610)
| PDB | External Database | Details |
|---|---|---|
| Met -20 | - | initiating methionine |
| Ala -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Lys -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Pro -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Leu 551 | - | expression tag |
| Glu 552 | - | expression tag |
| Gly 553 | - | expression tag |
| Ser 554 | - | expression tag |
| Asp 555 | - | expression tag |
| Glu 556 | - | expression tag |
| Val 557 | - | expression tag |
| Asp 558 | - | expression tag |
| Ala 559 | - | expression tag |
| Val 560 | - | expression tag |
| Glu 561 | - | expression tag |
| Gly 562 | - | expression tag |
| Ser 563 | - | expression tag |
| His 564 | - | expression tag |
| His 565 | - | expression tag |
| His 566 | - | expression tag |
| His 567 | - | expression tag |
| His 568 | - | expression tag |
| His 569 | - | expression tag |
| His 570 | - | expression tag |
| His 571 | - | expression tag |
| His 572 | - | expression tag |
| His 573 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 278981.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 4127.9 | |
| All* | Total formula weight | 283109.4 |
