6P0R
Methyltransferase domain of human suppressor of variegation 3-9 homolog 2 (SUV39H2) in complex with OTS186935 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone-lysine N-methyltransferase SUV39H2 | polymer | 299 | 33923.5 | 2 | UniProt (Q9H5I1) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (Human) | Histone H3-K9 methyltransferase 2,H3-K9-HMTase 2,Lysine N-methyltransferase 1B,Suppressor of variegation 3-9 homolog 2,Su(var)3-9 homolog 2 |
| 2 | C, I (A, B) | (3S)-1-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]-N-[(pyridin-4-yl)methyl]pyrrolidin-3-amine | non-polymer | 464.0 | 2 | Chemie (NM4) | |||
| 3 | D, E, F, G, J... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 4 | H, M (A, B) | UNKNOWN ATOM OR ION | non-polymer | 65.4 | 2 | Chemie (UNX) | |||
| 5 | N, O (A, B) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67847.0 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1516.6 | |
| All* | Total formula weight | 69363.6 |
