6OZW

Crystal structure of the 65-kilodalton amino-terminal fragment of DNA topoisomerase I from Streptococcus mutans

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA topoisomerase 1	polymer	595	67783.4	1	UniProt (Q8DUD3) Pfam (PF01751) Pfam (PF01131) In PDB	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	DNA topoisomerase I
2	A	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
3	A	FORMIC ACID	non-polymer		46.0	14	Chemie (FMT)
4		water	water		18.0	313	Chemie (HOH)

Sequence modifications

A: 1 - 575 (UniProt: Q8DUD3)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	67783.4
Non-Polymers*	Number of molecules	20
	Total formula weight	790.2
All*	Total formula weight	68573.6

*Water molecules are not included.