Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003916 | molecular_function | DNA topoisomerase activity |
| A | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
| A | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 601 |
| Chain | Residue |
| A | ARG157 |
| A | HOH789 |
| A | HOH968 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 602 |
| Chain | Residue |
| A | ARG158 |
| A | ARG162 |
| A | HOH864 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | ARG318 |
| A | HOH833 |
| A | HOH880 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 604 |
| Chain | Residue |
| A | ILE193 |
| A | ARG196 |
| A | GLU197 |
| A | HOH827 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 605 |
| Chain | Residue |
| A | ARG157 |
| A | ASP161 |
| A | ARG184 |
| A | HOH949 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 606 |
| Chain | Residue |
| A | ASN74 |
| A | GLY79 |
| A | GLU199 |
| A | HOH795 |
| A | HOH814 |
| A | HOH964 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 607 |
| Chain | Residue |
| A | ASP102 |
| A | ARG318 |
| A | SER489 |
| A | HOH832 |
| A | HOH866 |
| A | HOH894 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 608 |
| Chain | Residue |
| A | ASN415 |
| A | GLY416 |
| A | HOH727 |
| A | HOH753 |
| A | HOH755 |
| A | HOH803 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 609 |
| Chain | Residue |
| A | ARG196 |
| A | TYR471 |
| A | HOH760 |
| A | HOH829 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 610 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 611 |
| Chain | Residue |
| A | LYS175 |
| A | LEU523 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 612 |
| Chain | Residue |
| A | ASN129 |
| A | THR315 |
| A | TYR316 |
| A | HIS361 |
| A | GLU362 |
| A | ALA363 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 613 |
| Chain | Residue |
| A | ASP212 |
| A | LYS291 |
| A | LYS382 |
| A | ASP383 |
| A | GLU461 |
| A | FMT620 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 614 |
| Chain | Residue |
| A | LYS201 |
| A | LYS201 |
| A | HOH721 |
| A | HOH801 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue FMT A 616 |
| Chain | Residue |
| A | GLU69 |
| A | ASP152 |
| A | TRP554 |
| A | GLN555 |
| A | HOH764 |
| A | HOH957 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 617 |
| Chain | Residue |
| A | GLU36 |
| A | GLY40 |
| A | ARG41 |
| A | HOH845 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue FMT A 618 |
| Chain | Residue |
| A | HIS114 |
| A | ASP117 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue FMT A 619 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue FMT A 620 |
| Chain | Residue |
| A | LYS291 |
| A | GLU461 |
| A | FMT613 |
Functional Information from PROSITE/UniProt
| site_id | PS00396 |
| Number of Residues | 24 |
| Details | TOPO_IA_1 Topoisomerase (Topo) IA-type active site signature. QqLYEgirlgsngqqglITYmRTD |
| Chain | Residue | Details |
| A | GLN297-ASP320 | |
