6OZQ
Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo containing an inosine after a 100 min soak in 10 mM Mn2+ and K+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Endonuclease V | polymer | 253 | 28050.5 | 2 | UniProt (Q8C9A2) Pfam (PF04493) In PDB | Mus musculus (Mouse) | |
| 2 | C, D | DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3') | polymer | 23 | 7293.4 | 2 | synthetic construct | ||
| 3 | A, B, C, D | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 7 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 253 (UniProt: Q8C9A2)
| PDB | External Database | Details |
|---|---|---|
| Met 155 | Lys 155 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 70687.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 880.2 | |
| All* | Total formula weight | 71567.9 |
