6OZF
Crystal structure of Thermotoga maritima (Tm) Endonuclease V (D110N) in complex with a 12mer DNA containing an inosine followed by a ribo-adenosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endonuclease V | polymer | 225 | 25635.0 | 2 | UniProt (Q9X2H9) Pfam (PF04493) | Thermotoga maritima | Deoxyinosine 3'endonuclease,Deoxyribonuclease V,DNase V |
| 2 | C, D (C, D) | DNA/RNA (5'-D(P*AP*AP*TP*GP*I)-R(P*A)-D(P*GP*AP*TP*GP*CP*T)-3') | polymer | 12 | 3727.4 | 2 | synthetic construct | ||
| 3 | E, G, M, O (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | F, L (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | H, I (B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | J, N (B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | K (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 225 (UniProt: Q9X2H9)
| PDB | External Database | Details |
|---|---|---|
| Asn 110 | Asp 110 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58724.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 708.8 | |
| All* | Total formula weight | 59433.6 |
