6OYL

The structure of the PP2A B56 subunit KIF4A complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	polymer	355	41667.2	1	UniProt (Q13362) Pfam (PF01603)	Homo sapiens (Human)	PP2A B subunit isoform B'-gamma,PP2A B subunit isoform B56-gamma,PP2A B subunit isoform PR61-gamma,PP2A B subunit isoform R5-gamma,Renal carcinoma antigen NY-REN-29
2	B (B)	Chromosome-associated kinesin KIF4A	polymer	44	4966.6	1	UniProt (O95239)	Homo sapiens (Human)	Chromokinesin-A
3	C (A)	water	water		18.0	7	Chemie (HOH)

Sequence modifications

A: 31 - 380 (UniProt: Q13362)

PDB	External Database	Details
Gly 26	-	expression tag
His 27	-	expression tag
Met 28	-	expression tag
Gly 29	-	expression tag
Ser 30	-	expression tag

B: 1192 - 1232 (UniProt: O95239)

PDB	External Database	Details
Gly 1189	-	expression tag
His 1190	-	expression tag
Met 1191	-	expression tag
Leu 1224	Cys 1224	engineered mutation
Glu 1225	Ser 1225	engineered mutation
Pro 1231	Ala 1231	engineered mutation
Glu 1232	His 1232	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	46633.8
All*	Total formula weight	46633.8

*Water molecules are not included.