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6OY8

Crystal structure of Y99G mutant of human macrophage migration inhibitory factor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CMacrophage migration inhibitory factorpolymer11412248.93UniProt (P14174)
Pfam (PF01187)
In PDB
Homo sapiens (Human)MIF,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,Phenylpyruvate tautomerase
2A, B, CSULFATE IONnon-polymer96.13Chemie (SO4)
3A, BISOPROPYL ALCOHOLnon-polymer60.12Chemie (IPA)
4A, B, CGLYCEROLnon-polymer92.14Chemie (GOL)
5waterwater18.0316Chemie (HOH)
Sequence modifications
A, B, C: 1 - 114 (UniProt: P14174)
PDBExternal DatabaseDetails
Gly 99Tyr 100engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight36746.8
Non-Polymers*Number of molecules9
Total formula weight776.8
All*Total formula weight37523.6
*Water molecules are not included.

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PDB entries from 2024-06-12

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