6OXW
HIV-1 Protease NL4-3 WT in Complex with LR-100
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Protease NL4-3 | polymer | 99 | 10831.8 | 2 | UniProt (Q8ULI9) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 2 | C (A) | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[(2-ethylbutyl)({4-[(1R)-1-hydroxyethyl]phenyl}sulfonyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate | non-polymer | 604.8 | 1 | Chemie (NFJ) | |||
| 3 | D, E (B, A) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 99 (UniProt: Q8ULI9)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21663.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 604.8 | |
| All* | Total formula weight | 22268.4 |
