6OX5
A SETD3 Mutant (N255A) in Complex with an Actin Peptide with His73 Replaced with Lysine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | Y | Actin Peptide | polymer | 18 | 2154.4 | 1 | UniProt (P60709) In PDB | Homo sapiens | |
| 2 | A | Actin-histidine N-methyltransferase | polymer | 599 | 67710.5 | 1 | UniProt (Q86TU7) Pfam (PF00856) Pfam (PF09273) In PDB | Homo sapiens (Human) | SET domain-containing protein 3,hSETD3 |
| 3 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
Y: 66 - 83 (UniProt: P60709)
A: 0 - 593 (UniProt: Q86TU7)
| PDB | External Database | Details |
|---|---|---|
| Lys 73 | His 73 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ala 255 | Asn 256 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69864.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 881.0 | |
| All* | Total formula weight | 70745.9 |
