6OWO

CRYO-EM STRUCTURE OF PHOSPHORYLATED AP-2 CORE BOUND TO NECAP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	AP-2 complex subunit alpha-2	polymer	621	69656.3	1	Pfam (PF01602) UniProt (by SIFTS) (P17427) In PDB	Mus musculus (Mouse)
2	B	AP-2 complex subunit beta	polymer	591	66953.2	1	UniProt (Q9DBG3) Pfam (PF01602) In PDB	Mus musculus (Mouse)	AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit
3	M	AP-2 complex subunit mu	polymer	435	49806.6	1	UniProt (P84091) Pfam (PF01217) Pfam (PF00928) In PDB	Mus musculus (Mouse)	AP-2 mu chain,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,Mu2-adaptin,Plasma membrane adaptor AP-2 50 kDa protein
4	S	AP-2 complex subunit sigma	polymer	142	17038.7	1	UniProt (P62744) Pfam (PF01217) In PDB	Rattus norvegicus (Rat)	Adaptor protein complex AP-2 subunit sigma,Adaptor-related protein complex 2 subunit sigma,Clathrin assembly protein 2 sigma small chain,Clathrin coat assembly protein AP17,Clathrin coat-associated protein AP17,Plasma membrane adaptor AP-2 17 kDa protein,Sigma-adaptin 3b,Sigma2-adaptin
5	N	Adaptin ear-binding coat-associated protein 2	polymer	266	28629.9	1	UniProt (Q9D1J1) Pfam (PF07933) In PDB	Mus musculus (Mouse)	NECAP endocytosis-associated protein 2,NECAP-2

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	232084.7
All*	Total formula weight	232084.7

*Water molecules are not included.