6OT5
Structure of the TRPV3 K169A sensitized mutant in the presence of 2-APB at 3.6 A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Transient receptor potential cation channel subfamily V member 3,Transient receptor potential cation channel subfamily V member 3 | polymer | 719 | 82981.9 | 4 | UniProt (Q8NET8) Pfam (PF12796) Pfam (PF00023) Pfam (PF00520) In PDB | Homo sapiens (Human) | TrpV3,Vanilloid receptor-like 3,VRL-3 |
2 | A, B, C, D | 2-aminoethyl diphenylborinate | non-polymer | 225.1 | 4 | Chemie (FZ4) |
Sequence modifications
A, B, C, D: 1 - 12 (PDB: 6OT5)
A, B, C, D: 110 - 790 (UniProt: Q8NET8)
A, B, C, D: 110 - 790 (UniProt: Q8NET8)
PDB | External Database | Details |
---|---|---|
Ala 169 | Lys 169 | engineered mutation |
Val 791 | - | expression tag |
Asp 792 | - | expression tag |
Ala 793 | - | expression tag |
Gly 794 | - | expression tag |
Leu 795 | - | expression tag |
Glu 796 | - | expression tag |
Val 797 | - | expression tag |
Leu 798 | - | expression tag |
Phe 799 | - | expression tag |
Gln 800 | - | expression tag |
Gly 801 | - | expression tag |
Asp 802 | - | expression tag |
Tyr 803 | - | expression tag |
Lys 804 | - | expression tag |
Asp 805 | - | expression tag |
Asp 806 | - | expression tag |
Asp 807 | - | expression tag |
Asp 808 | - | expression tag |
Lys 809 | - | expression tag |
Ala 810 | - | expression tag |
His 811 | - | expression tag |
His 812 | - | expression tag |
His 813 | - | expression tag |
His 814 | - | expression tag |
His 815 | - | expression tag |
His 816 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 331927.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 900.4 | |
All* | Total formula weight | 332827.8 |