6ONY
BRD2_Bromodomain1 complex with inhibitor 744
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 2 | polymer | 126 | 14885.3 | 2 | UniProt (P25440) Pfam (PF00439) | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | C, F (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 3 | D, E (A, B) | N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl]-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide | non-polymer | 491.6 | 2 | Chemie (HWV) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 73 - 194 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Gly 69 | - | expression tag |
| Ser 70 | - | expression tag |
| His 71 | - | expression tag |
| Met 72 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29770.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1107.2 | |
| All* | Total formula weight | 30877.9 |
