6ONJ
Crystal structure of PPARgamma ligand binding domain in complex with TRAP220 peptide and agonist rosiglitazone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor gamma | polymer | 275 | 31449.5 | 1 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
| 2 | B (C) | Mediator of RNA polymerase II transcription subunit 1, TRAP220 Coactivator Peptide | polymer | 19 | 2197.5 | 1 | UniProt (Q15648) | Homo sapiens (Human) | Activator-recruited cofactor 205 kDa component,ARC205,Mediator complex subunit 1,Peroxisome proliferator-activated receptor-binding protein,PPAR-binding protein,Thyroid hormone receptor-associated protein complex 220 kDa component,Trap220,Thyroid receptor-interacting protein 2,TRIP-2,Vitamin D receptor-interacting protein complex component DRIP205,p53 regulatory protein RB18A |
| 3 | C (A) | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL) | non-polymer | 357.4 | 1 | Chemie (BRL) | |||
| 4 | D, E (A, C) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33647.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 357.4 | |
| All* | Total formula weight | 34004.5 |
