6OM3
Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E, M, Q | Histone H3.2 | polymer | 135 | 15303.9 | 4 | UniProt (P84233) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | |
2 | B, F, N, R | Histone H4 | polymer | 103 | 11394.4 | 4 | UniProt (P62799) Pfam (PF15511) In PDB | Xenopus laevis (African clawed frog) | |
3 | C, G, O, S | Histone H2A | polymer | 130 | 14109.4 | 4 | UniProt (Q6AZJ8) Pfam (PF00125) Pfam (PF16211) UniProt (by SIFTS) (P06897) In PDB | Xenopus laevis (African clawed frog) | |
4 | D, H, P, T | Histone H2B 1.1 | polymer | 126 | 13979.3 | 4 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | H2B1.1 |
5 | I, U | DNA (146-MER) | polymer | 146 | 44824.6 | 2 | synthetic construct | ||
6 | J, V | DNA (147-MER) | polymer | 147 | 45609.1 | 2 | synthetic construct | ||
7 | K, L, W, X | Origin recognition complex subunit 1 | polymer | 224 | 26067.5 | 4 | UniProt (P54784) Pfam (PF01426) In PDB | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Origin recognition complex 120 kDa subunit |
Sequence modifications
A, E, M, Q: 1 - 135 (UniProt: P84233)
D, H, P, T: 0 - 125 (UniProt: P02281)
K, L, W, X: 2 - 214 (UniProt: P54784)
PDB | External Database | Details |
---|---|---|
Ala 102 | Gly 103 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 32 | Ser 33 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ace 1 | - | acetylation |
Ile 79 | Leu 79 | engineered mutation |
Ala 215 | - | expression tag |
Ala 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
His 219 | - | expression tag |
His 220 | - | expression tag |
His 221 | - | expression tag |
His 222 | - | expression tag |
His 223 | - | expression tag |
His 224 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 24 |
Total formula weight | 504285.5 | |
All* | Total formula weight | 504285.5 |