6OJE
Dimeric structure of LRRK2 GTPase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Leucine-rich repeat serine/threonine-protein kinase 2 | polymer | 206 | 23511.1 | 2 | UniProt (Q5S007) Pfam (PF08477) | Homo sapiens (Human) | Dardarin, LRRK2 |
| 2 | C, E, F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | D, G (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A, B: 1329 - 1520 (UniProt: Q5S007)
| PDB | External Database | Details |
|---|---|---|
| Met 1315 | - | initiating methionine |
| Gly 1316 | - | expression tag |
| Ser 1317 | - | expression tag |
| Ser 1318 | - | expression tag |
| His 1319 | - | expression tag |
| His 1320 | - | expression tag |
| His 1321 | - | expression tag |
| His 1322 | - | expression tag |
| His 1323 | - | expression tag |
| His 1324 | - | expression tag |
| Ser 1325 | - | expression tag |
| Gln 1326 | - | expression tag |
| Asp 1327 | - | expression tag |
| Pro 1328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47022.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 983.6 | |
| All* | Total formula weight | 48005.9 |
