6OIJ
Muscarinic acetylcholine receptor 1-G11 protein complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein subunit alpha-11 | polymer | 353 | 41271.1 | 1 | UniProt (A0A3B3ITX3) UniProt (P29992) Pfam (PF00503) | Homo sapiens (Human) | G-protein subunit alpha-11,Guanine nucleotide-binding protein G(y) subunit alpha |
| 2 | B (R) | Muscarinic acetylcholine receptor M1 | polymer | 363 | 41241.3 | 1 | UniProt (P11229) Pfam (PF00001) | Homo sapiens (Human) | |
| 3 | C (H) | Antibody fragment | polymer | 256 | 27340.5 | 1 | Mus musculus (Mouse) | ||
| 4 | D (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) Pfam (PF25391) | Homo sapiens (Human) | Transducin beta chain 1 |
| 5 | E (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (Human) | G gamma-I |
| 6 | F (R) | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium | non-polymer | 197.3 | 1 | Chemie (IXO) PubChem (10104167) | |||
| 7 | G, H (R) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (45489984) PubChem (363416) PubChem (60078761) PubChem (500055) PubChem (73440805) PubChem (57163942) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (99567469) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (13301926) PubChem (13301927) PubChem (124914595) PubChem (124914596) PubChem (155804219) PubChem (169132514) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A: 1 - 29 (UniProt: A0A3B3ITX3)
A: 36 - 359 (UniProt: P29992)
R: 2 - 344 (UniProt: P11229)
R: 345 - 460 (UniProt: P11229)
B: 2 - 340 (UniProt: P62873)
A: 36 - 359 (UniProt: P29992)
R: 2 - 344 (UniProt: P11229)
| PDB | External Database | Details |
|---|---|---|
| Asp -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Lys -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Gln 2 | Asn 2 | engineered mutation |
| Gln 12 | Asn 12 | engineered mutation |
| Gln 110 | Asn 110 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| His 461 | - | expression tag |
| His 462 | - | expression tag |
| His 463 | - | expression tag |
| His 464 | - | expression tag |
| His 465 | - | expression tag |
| His 466 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 155442.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1170.7 | |
| All* | Total formula weight | 156612.8 |
