6OIJ
Muscarinic acetylcholine receptor 1-G11 protein complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein subunit alpha-11 | polymer | 353 | 41271.1 | 1 | UniProt (A0A3B3ITX3) UniProt (P29992) Pfam (PF00503) In PDB | Homo sapiens (Human) | G-protein subunit alpha-11,Guanine nucleotide-binding protein G(y) subunit alpha |
2 | R | Muscarinic acetylcholine receptor M1 | polymer | 363 | 41241.3 | 1 | UniProt (P11229) Pfam (PF00001) In PDB | Homo sapiens (Human) | |
3 | H | Antibody fragment | polymer | 256 | 27340.5 | 1 | Mus musculus (Mouse) | ||
4 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 345 | 37728.2 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (Human) | Transducin beta chain 1 |
5 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (Human) | G gamma-I |
6 | R | 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium | non-polymer | 197.3 | 1 | Chemie (IXO) | |||
7 | R | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) |
Sequence modifications
A: 1 - 29 (UniProt: A0A3B3ITX3)
A: 36 - 359 (UniProt: P29992)
R: 2 - 344 (UniProt: P11229)
R: 345 - 460 (UniProt: P11229)
B: 2 - 340 (UniProt: P62873)
A: 36 - 359 (UniProt: P29992)
R: 2 - 344 (UniProt: P11229)
PDB | External Database | Details |
---|---|---|
Asp -8 | - | expression tag |
Tyr -7 | - | expression tag |
Lys -6 | - | expression tag |
Asp -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Ala -1 | - | expression tag |
Ala 0 | - | expression tag |
Ala 1 | - | expression tag |
Gln 2 | Asn 2 | engineered mutation |
Gln 12 | Asn 12 | engineered mutation |
Gln 110 | Asn 110 | engineered mutation |
PDB | External Database | Details |
---|---|---|
His 461 | - | expression tag |
His 462 | - | expression tag |
His 463 | - | expression tag |
His 464 | - | expression tag |
His 465 | - | expression tag |
His 466 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Ser 0 | - | expression tag |
Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 155442.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1170.7 | |
All* | Total formula weight | 156612.8 |