6OHS

Structure of compound 3 (ML299) bound human Phospholipase D2 catalytic domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Phospholipase D2	polymer	640	72846.8	4	UniProt (O14939) Pfam (PF00614) Pfam (PF13091)	Homo sapiens (Human)	hPLD2,Choline phosphatase 2,PLD1C,Phosphatidylcholine-hydrolyzing phospholipase D2
2	E, F, G, H (A, B, C, D)	4-bromo-N-{(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl}benzamide	non-polymer		489.4	4	Chemie (MJY)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	291387.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1957.5
All*	Total formula weight	293344.6

*Water molecules are not included.