6OFI
CRYSTAL STRUCTURE OF the RV144 C1-C2 SPECIFIC ANTIBODY CH55 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G | clade A/E 93TH057 HIV-1 gp120 core | polymer | 355 | 39356.6 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
| 2 | H | CH55 Fab heavy chain | polymer | 223 | 24004.1 | 1 | Homo sapiens (human) | ||
| 3 | L | CH55 Fab light chain | polymer | 215 | 23444.9 | 1 | Homo sapiens (human) | ||
| 4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) |
Sequence modifications
G: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Val 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86805.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2212.1 | |
| All* | Total formula weight | 89017.7 |
