6OET
Cryo-EM structure of mouse RAG1/2 STC complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | V(D)J recombination-activating protein 1 | polymer | 1040 | 119388.4 | 2 | UniProt (P15919) Pfam (PF12560) Pfam (PF00097) Pfam (PF10426) Pfam (PF12940) | Mus musculus (Mouse) | RAG-1 |
| 2 | B, D (B, D) | V(D)J recombination-activating protein 2 | polymer | 527 | 59138.4 | 2 | UniProt (P21784) Pfam (PF03089) Pfam (PF13341) | Mus musculus (Mouse) | RAG-2 |
| 3 | E (F) | DNA (50-MER) | polymer | 50 | 15521.9 | 1 | Escherichia coli K-12 | ||
| 4 | F, G (I, J) | DNA (5'-D(*CP*CP*TP*GP*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*G)-3') | polymer | 15 | 4577.0 | 2 | Escherichia coli K-12 | ||
| 5 | H (G) | DNA (59-MER) | polymer | 61 | 18762.0 | 1 | Escherichia coli K-12 | ||
| 6 | I (L) | DNA (30-MER) | polymer | 30 | 9138.9 | 1 | Escherichia coli K-12 | ||
| 7 | J (M) | DNA (39-MER) | polymer | 41 | 12655.2 | 1 | Escherichia coli K-12 | ||
| 8 | K, M (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 9 | L, N (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, C: 1 - 1040 (UniProt: P15919)
| PDB | External Database | Details |
|---|---|---|
| Gln 962 | Glu 962 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 422285.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 211.0 | |
| All* | Total formula weight | 422496.4 |
