6OD5
Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence with 5-carboxylcytosines
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (A, B, C, D) | Transcription factor 4 | polymer | 62 | 7401.7 | 4 | UniProt (P15884) Pfam (PF00010) | Homo sapiens (Human) | TCF-4, Class B basic helix-loop-helix protein 19, bHLHb19, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2 |
| 2 | C, D, G, H (X, Y, E, F) | DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3') | polymer | 12 | 3751.4 | 4 | Homo sapiens | ||
| 3 | I, K, M, N, O (A, B, C, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | L (X) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | P, Q, R, S, T... (A, B, X, Y, C...) | water | water | 18.0 | 136 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 569 - 628 (UniProt: P15884)
| PDB | External Database | Details |
|---|---|---|
| His 567 | - | expression tag |
| Met 568 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 44612.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 437.9 | |
| All* | Total formula weight | 45050.5 |
